Ontology highlight
ABSTRACT:
SUBMITTER: Teigland CL
PROVIDER: S-EPMC3737279 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Teigland C L CL Parrott R E RE Buckley R H RH
Bone marrow transplantation 20130211 8
SCID is a fatal syndrome caused by mutations in at least 13 different genes. It is characterized by the absence of T cells. Immune reconstitution can be achieved through nonablative related donor BMT. However, the first transplant may not provide sufficient immunity. In these cases, booster transplants may be helpful. A prospective/retrospective study was conducted of 49 SCID patients (28.7% of 171 SCIDs transplanted over 30 years) who had received booster transplants to define the long-term out ...[more]