Platelets as cellular effectors of inflammation in vascular diseases.
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ABSTRACT:
SUBMITTER: Rondina MT
PROVIDER: S-EPMC3738064 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Publications
Platelets as cellular effectors of inflammation in vascular diseases.
Rondina Matthew T MT Weyrich Andrew S AS Zimmerman Guy A GA
Circulation research 20130501 11
Platelets are chief effector cells in hemostasis. In addition, they are multifaceted inflammatory cells with functions that span the continuum from innate immune responses to adaptive immunity. Activated platelets have key thromboinflammatory activities in a variety of vascular disorders and vasculopathies. Recently identified inflammatory and immune activities provide insights into the biology of these versatile blood cells that are directly relevant to human vascular diseases. ...[more]
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