Ontology highlight
ABSTRACT:
SUBMITTER: Yildirim I
PROVIDER: S-EPMC3738067 | biostudies-literature | 2005 Oct
REPOSITORIES: biostudies-literature
Yildirim Ilyas I Turner Douglas H DH
Biochemistry 20051001 40
Some experimental results for the thermodynamics of RNA folding cannot be explained by simple pairwise hydrogen-bonding models. Such effects include the stabilities of isoguanosine-isocytidine (iG-iC) base pairs and of various 2 x 2 nucleotide internal loops. Presumably, these results can be explained by base stacking effects, which can be partitioned into Coulombic and overlap effects. We review experimental measurements that provide benchmarks for testing the approximations and theories used f ...[more]