Ontology highlight
ABSTRACT:
SUBMITTER: Xu H
PROVIDER: S-EPMC3742238 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Xu Hongliang H Yao Nannan N Xu Haoran H Wang Tianshi T Li Guiying G Li Zhengqiang Z
International journal of molecular sciences 20130709 7
This study investigated the interaction between eupatorin and bovine serum albumin (BSA) using ultraviolet-visible (UV-vis) absorption, fluorescence, synchronous fluorescence, circular dichroism (CD) spectroscopies, and molecular modeling at pH 7.4. Results of UV-vis and fluorescence spectroscopies illustrated that BSA fluorescence was quenched by eupatorin via a static quenching mechanism. Thermodynamic parameters revealed that hydrophobic and electrostatic interactions played major roles in th ...[more]