Genomically intact endogenous feline leukemia viruses of recent origin.
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ABSTRACT:
SUBMITTER: Roca AL
PROVIDER: S-EPMC374283 | biostudies-literature | 2004 Apr
REPOSITORIES: biostudies-literature
Publications
Genomically intact endogenous feline leukemia viruses of recent origin.
Roca Alfred L AL Pecon-Slattery Jill J O'Brien Stephen J SJ
Journal of virology 20040401 8
We isolated and sequenced two complete endogenous feline leukemia viruses (enFeLVs), designated enFeLV-AGTT and enFeLV-GGAG. In enFeLV-AGTT, the open reading frames are reminiscent of a functioning FeLV genome, and the 5' and 3' long terminal repeat sequences are identical. Neither endogenous provirus is genetically fixed in cats but polymorphic, with 8.9 and 15.2% prevalence for enFeLV-AGTT and enFeLV-GGAG, respectively, among a survey of domestic cats. Neither provirus was found in the genomes ...[more]
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