Ontology highlight
ABSTRACT:
SUBMITTER: Du Y
PROVIDER: S-EPMC3743434 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Du Yunfeng Y Navab Mohamad M Shen Melody M Hill James J Pakbin Payam P Sioutas Constantinos C Hsiai Tzung K TK Li Rongsong R
Biochemical and biophysical research communications 20130607 3
Exposure to airborne particulate pollutants is intimately linked to vascular oxidative stress and inflammatory responses with clinical relevance to atherosclerosis. Particulate matter (PM) has been reported to induce endothelial dysfunction and atherosclerosis. Here, we tested whether ambient ultrafine particles (UFP, diameter <200 nm) modulate eNOS activity in terms of nitric oxide (NO) production via protein S-glutathionylation. Treatment of human aortic endothelial cells (HAEC) with UFP signi ...[more]