Ontology highlight
ABSTRACT:
SUBMITTER: Saito Y
PROVIDER: S-EPMC3744069 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Saito Yohei Y Kojima Takuya T Takahashi Naoki N
Biology open 20130620 8
The liver, gall bladder, and ventral pancreas are formed from the posterior region of the ventral foregut. After hepatic induction, Sox17+/Pdx1+ pancreatobiliary common progenitor cells differentiate into Sox17+/Pdx1- gall bladder progenitors and Sox17-/Pdx1+ ventral pancreatic progenitors, but the cell-extrinsic signals that regulate this differentiation process are unknown. This study shows that the septum transversum mesenchyme (STM) grows in the posterior direction after E8.5, becoming adjac ...[more]