Resilin-Based Hybrid Hydrogels for Cardiovascular Tissue Engineering.
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ABSTRACT:
SUBMITTER: McGann CL
PROVIDER: S-EPMC3744378 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
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Resilin-Based Hybrid Hydrogels for Cardiovascular Tissue Engineering.
McGann Christopher L CL Levenson Eric A EA Kiick Kristi L KL
Macromolecules 20130101 2
The outstanding elastomeric properties of natural resilin, an insect protein, have motivated the engineering of resilin-like polypeptides (RLPs) as a potential material for cardiovascular tissue engineering. The RLPs, which incorporate biofunctional domains for cell-matrix interactions, are cross-linked into RLP-PEG hybrid hydrogels via a Michael-type addition of cysteine residues on the RLP with vinyl sulfones of an end-functionalized multi-arm star PEG. Oscillatory rheology indicated the usefu ...[more]
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