HVEM gene polymorphisms are associated with sporadic breast cancer in Chinese women.
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ABSTRACT:
SUBMITTER: Li D
PROVIDER: S-EPMC3745383 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
HVEM gene polymorphisms are associated with sporadic breast cancer in Chinese women.
Li Dalin D Fu Zhenkun Z Chen Shuang S Yuan Weiguang W Liu Yanhong Y Li Liqun L Pang Da D Li Dianjun D
PloS one 20130816 8
As a costimulatory molecule, Herpesvirus entry mediator (HVEM) can bind with several costimulatory members, thus HVEM plays different roles in T cell immunity. HVEM and its ligands have been involved in the pathogenesis of various autoimmune, inflammatory diseases and tumors. In the current study, we conducted a case-control study comparing polymorphisms of HVEM and breast cancer. Subjects included 575 females with breast cancer and 604 age-matched healthy controls. Six HVEM SNPs (rs2281852, rs1 ...[more]
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