Preserving neural function under extreme scaling.
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ABSTRACT:
SUBMITTER: Cuntz H
PROVIDER: S-EPMC3747245 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Preserving neural function under extreme scaling.
Cuntz Hermann H Forstner Friedrich F Schnell Bettina B Ammer Georg G Raghu Shamprasad Varija SV Borst Alexander A
PloS one 20130819 8
Important brain functions need to be conserved throughout organisms of extremely varying sizes. Here we study the scaling properties of an essential component of computation in the brain: the single neuron. We compare morphology and signal propagation of a uniquely identifiable interneuron, the HS cell, in the blowfly (Calliphora) with its exact counterpart in the fruit fly (Drosophila) which is about four times smaller in each dimension. Anatomical features of the HS cell scale isometrically an ...[more]
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