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Impact of lung transplantation on recipient quality of life: a serial, prospective, multicenter analysis through the first posttransplant year.


ABSTRACT:

Background

Quality of life (QOL) is an important but understudied outcome after lung transplantation. Previous cross-sectional, single-center studies suggest improved QOL, but few prior longitudinal multicenter data exist regarding the effect of transplantation on the patient’s QOL.

Methods

We hypothesized that lung transplantation confers a 1-year QOL benefit in both physical and psychologic well-being; we further hypothesized that the magnitude of benefit would vary by sex, native disease, age, or type of transplant operation. To test these hypotheses, we conducted a secondary analysis using QOL data prospectively and serially measured with the Medical Outcomes Study 36-Item Short-Form Health Survey, version 2 (SF-36) in a multicenter cytomegalovirus prevention clinical tr

SUBMITTER: Finlen Copeland CA 

PROVIDER: S-EPMC3747721 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature