Dataset Information

Patients with COPD with higher levels of anxiety are more physically active.

ABSTRACT:

Background

Physical activity (PA) has been found to be an excellent predictor of mortality beyond traditional measures in COPD. We aimed to determine the association between depression and anxiety with accelerometry-based PA in patients with COPD.

Methods

We performed a cross-sectional analysis of baseline data from 148 stable patients with COPD enrolled in an ongoing, longitudinal, observational study. We measured PA (total daily step count) with a Stepwatch Activity Monitor over 7 days, depression and anxiety with the Hospital Anxiety and Depression Scales (HADSs), dyspnea with the Shortness of Breath Questionnaire, and functional capacity with the 6-min walk test.

Results

Increased anxiety was associated with higher levels of PA such that for every one-point increase in the HADS-Anxiety score there was a corresponding increase of 288 step counts per day (β=288 steps, P<.001), after adjusting for all other variables. Higher levels of depressive symptoms were associated with lower PA (β=-176 steps, P=.02) only when anxiety was in the model. The interaction term for anxiety and depression approached significance (β=26, P=.10), suggesting that higher levels of anxiety mitigate the negative effects of depression on PA.

Conclusions

The increased PA associated with anxiety in COPD is, to our knowledge, a novel finding. However, it is unclear whether anxious patients with COPD are more restless, and use increased psychomotor activity as a coping mechanism, or whether those with COPD who push themselves to be more physically active experience more anxiety symptoms. Future studies should evaluate for anxiety and PA to better inform how to improve clinical outcomes.

Trial registry

Clinicaltrials.gov; No.: NCT01074515; URL: www.clinicaltrials.gov.

SUBMITTER: Nguyen HQ

PROVIDER: S-EPMC3747724 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature

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Publications

Patients with COPD with higher levels of anxiety are more physically active.

Nguyen Huong Q HQ Fan Vincent S VS Herting Jerald J Lee Jungeun J Fu Musetta M Chen Zijing Z Borson Soo S Kohen Ruth R Matute-Bello Gustavo G Pagalilauan Genevieve G Adams Sandra G SG

Chest 20130701 1

<h4>Background</h4>Physical activity (PA) has been found to be an excellent predictor of mortality beyond traditional measures in COPD. We aimed to determine the association between depression and anxiety with accelerometry-based PA in patients with COPD.<h4>Methods</h4>We performed a cross-sectional analysis of baseline data from 148 stable patients with COPD enrolled in an ongoing, longitudinal, observational study. We measured PA (total daily step count) with a Stepwatch Activity Monitor over ...[more]

PMID: 23370503

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Dataset Information

Patients with COPD with higher levels of anxiety are more physically active.

Background

Methods

Results

Conclusions

Trial registry

Publications

Patients with COPD with higher levels of anxiety are more physically active.

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