Unknown

Dataset Information

0

Self-report and clinician-rated measures of depression severity: can one replace the other?


ABSTRACT: It has been suggested that clinician-rated scales and self-report questionnaires may be interchangeable in the measurement of depression severity, but it has not been tested whether clinically significant information is lost when assessment is restricted to either clinician-rated or self-report instruments. The aim of this study is to test whether self-report provides information relevant to short-term treatment outcomes that is not captured by clinician-rating and vice versa.In genome-based drugs for depression (GENDEP), 811 patients with major depressive disorder treated with escitalopram or nortriptyline were assessed with the clinician-rated Montgomery-Åsberg Depression Rating Scale (MADRS), Hamilton Rating Scale for Depression (HRSD), and the self-report Beck Depression Inventory (BDI). In sequenced treatment alternatives to relieve depression (STAR*D), 4,041 patients treated with citalopram were assessed with the clinician-rated and self-report versions of the Quick Inventory of Depressive Symptomatology (QIDS-C and QIDS-SR) in addition to HRSD.In GENDEP, baseline BDI significantly predicted outcome on MADRS/HRSD after adjusting for baseline MADRS/HRSD, explaining additional 3 to 4% of variation in the clinician-rated outcomes (both P < .001). Likewise, each clinician-rated scale significantly predicted outcome on BDI after adjusting for baseline BDI and explained additional 1% of variance in the self-reported outcome (both P < .001). The results were confirmed in STAR*D, where self-report and clinician-rated versions of the same instrument each uniquely contributed to the prediction of treatment outcome.Complete assessment of depression should include both clinician-rated scales and self-reported measures.

SUBMITTER: Uher R 

PROVIDER: S-EPMC3750710 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

Self-report and clinician-rated measures of depression severity: can one replace the other?

Uher Rudolf R   Perlis Roy H RH   Placentino Anna A   Dernovšek Mojca Zvezdana MZ   Henigsberg Neven N   Mors Ole O   Maier Wolfgang W   McGuffin Peter P   Farmer Anne A  

Depression and anxiety 20120829 12


<h4>Background</h4>It has been suggested that clinician-rated scales and self-report questionnaires may be interchangeable in the measurement of depression severity, but it has not been tested whether clinically significant information is lost when assessment is restricted to either clinician-rated or self-report instruments. The aim of this study is to test whether self-report provides information relevant to short-term treatment outcomes that is not captured by clinician-rating and vice versa.  ...[more]

Similar Datasets

| S-EPMC5271457 | biostudies-literature
| S-EPMC6614007 | biostudies-literature
| S-EPMC3922978 | biostudies-literature
| S-EPMC10582342 | biostudies-literature
| S-EPMC9287766 | biostudies-literature
| S-EPMC6083441 | biostudies-literature
| S-EPMC5663078 | biostudies-literature
| S-EPMC6086446 | biostudies-other
| S-EPMC4177165 | biostudies-literature
| S-EPMC9299700 | biostudies-literature