Ontology highlight
ABSTRACT:
SUBMITTER: Parodi A
PROVIDER: S-EPMC3751189 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Nature nanotechnology 20121216 1
The therapeutic efficacy of systemic drug-delivery vehicles depends on their ability to evade the immune system, cross the biological barriers of the body and localize at target tissues. White blood cells of the immune system--known as leukocytes--possess all of these properties and exert their targeting ability through cellular membrane interactions. Here, we show that nanoporous silicon particles can successfully perform all these actions when they are coated with cellular membranes purified f ...[more]