Ontology highlight
ABSTRACT:
SUBMITTER: Narayanan MM
PROVIDER: S-EPMC3751451 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Narayanan Manoj M MM Nair Chandrasekhar B CB Sanjeeva Shilpa K SK Rao Pv Subba PS Pullela Phani K PK Barrow Colin J CJ
Advances and applications in bioinformatics and chemistry : AABC 20130819
Viral neuraminidase inhibitors such as oseltamivir and zanamivir prevent early virus multiplication by blocking sialic acid cleavage on host cells. These drugs are effective for the treatment of a variety of influenza subtypes, including swine flu (H1N1). The binding site for these drugs is well established and they were designed based on computational docking studies. We show here that some common natural products have moderate inhibitory activity for H1N1 neuraminidase under docking studies. S ...[more]