Ontology highlight
ABSTRACT:
SUBMITTER: Hu Y
PROVIDER: S-EPMC3756056 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Hu Ying Y Bai Ling L Geiger Thomas T Goldberger Natalie N Walker Renard C RC Green Jeffery E JE Wakefield Lalage M LM Hunter Kent W KW
PloS one 20130828 8
Recent advances in genome wide transcriptional analysis have provided greater insights into the etiology and heterogeneity of breast cancer. Molecular signatures have been developed that stratify the conventional estrogen receptor positive or negative categories into subtypes that are associated with differing clinical outcomes. It is thought that the expression patterns of the molecular subtypes primarily reflect cell-of-origin or tumor driver mutations. In this study however, using a genetical ...[more]