Ontology highlight
ABSTRACT:
SUBMITTER: Tajima T
PROVIDER: S-EPMC3756183 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Tajima Toshihiro T Ishizu Katsura K Nakamura Akie A
Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology 20130426 2
The pituitary gland produces hormones that play important roles in both the development and homeostasis of the body. Ontogeny of the anterior and posterior pituitary is orchestrated by inputs from neighboring tissues, cellular signaling molecules and transcription factors. Disruption of expression or function of these factors has been implicated in the etiology of combined pituitary hormone deficiency (CPHD). These include the transcription factors HESX1, PROP1, POU1F1, LHX3, LHX4, OTX2, SOX2, S ...[more]