A powered bone marrow biopsy system versus manual methods: a systematic review and meta-analysis of randomised trials.

ABSTRACT: A significant number of bone marrow biopsies are performed annually. Outcomes of patient pain and sample size of biopsy are important issues as perception of patient pain is underestimated by clinicians and sample size assists in accurate diagnosis. Manual extraction of marrow biopsy is the main method used. Recently a powered system has been introduced. The objectives of this systematic review and meta-analysis were to determine if the powered system reduces patient pain and improves sample capture. A PubMed and Cochrane search for randomised controlled trials was undertaken comparing the powered system with manual methods. Risk of bias assessment and meta-analysis of outcomes using appropriate statistical methods were performed. Five randomised controlled trials were identified. Patient

SUBMITTER: Voigt J 

PROVIDER: S-EPMC3756462 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature