Ontology highlight
ABSTRACT:
SUBMITTER: Federau C
PROVIDER: S-EPMC3758329 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Federau Christian C Hagmann Patric P Maeder Philippe P Müller Markus M Meuli Reto R Stuber Matthias M O'Brien Kieran K
PloS one 20130830 8
Measurement of microvascular perfusion with Intravoxel Incoherent Motion (IVIM) MRI is gaining interest. Yet, the physiological influences on the IVIM perfusion parameters ("pseudo-diffusion" coefficient D*, perfusion fraction f, and flow related parameter fD*) remain insufficiently characterized. In this article, we hypothesize that D* and fD*, which depend on blood speed, should vary during the cardiac cycle. We extended the IVIM model to include time dependence of D* = D*(t), and demonstrate ...[more]