Evolutionary history of chordate PAX genes: dynamics of change in a complex gene family.
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ABSTRACT:
SUBMITTER: Paixao-Cortes VR
PROVIDER: S-EPMC3759438 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Evolutionary history of chordate PAX genes: dynamics of change in a complex gene family.
Paixão-Côrtes Vanessa Rodrigues VR Salzano Francisco Mauro FM Bortolini Maria Cátira MC
PloS one 20130902 9
Paired box (PAX) genes are transcription factors that play important roles in embryonic development. Although the PAX gene family occurs in animals only, it is widely distributed. Among the vertebrates, its 9 genes appear to be the product of complete duplication of an original set of 4 genes, followed by an additional partial duplication. Although some studies of PAX genes have been conducted, no comprehensive survey of these genes across the entire taxonomic unit has yet been attempted. In thi ...[more]
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