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ABSTRACT:
SUBMITTER: Deschout H
PROVIDER: S-EPMC3759922 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Deschout Hendrik H Martens Thomas T Vercauteren Dries D Remaut Katrien K Demeester Jo J De Smedt Stefaan C SC Neyts Kristiaan K Braeckmans Kevin K
International journal of molecular sciences 20130808 8
Interactions between objects inside living cells are often investigated by looking for colocalization between fluorescence microscopy images that are recorded in separate colours corresponding to the fluorescent label of each object. The fundamental limitation of this approach in the case of dynamic objects is that coincidental colocalization cannot be distinguished from true interaction. Instead, correlation between motion trajectories obtained by dual colour single particle tracking provides a ...[more]