Ontology highlight
ABSTRACT:
SUBMITTER: Dutkowski J
PROVIDER: S-EPMC3761421 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Dutkowski Janusz J Tiuryn Jerzy J
Journal of computational biology : a journal of computational molecular cell biology 20130809 9
Comparative approaches in genomics have long relied on rigorous mathematical models of sequence evolution. Such models provide the basis for formulating and solving well-defined computational problems, in turn yielding key insights into the evolutionary processes acting on the genome. Analogous model-based approaches for analyzing biological networks are still under development. Here we describe a model-based approach for estimating the probability of network rewiring events during evolution. Ou ...[more]