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A nosocomial outbreak of norovirus infection masquerading as clostridium difficile infection.


ABSTRACT: Noroviruses (NoVs) are increasingly being recognized as important enteric pathogens. At a university-based hospital, we investigated a nosocomial outbreak of NoV infection that was originally attributed to Clostridium difficile. We describe here the unique challenges of the identification of NoVs as the true etiologic pathogen in an outbreak occurring in a health care setting, where C. difficile infection is endemic, as well as the important lessons learned.

SUBMITTER: Koo HL 

PROVIDER: S-EPMC3761966 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature

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A nosocomial outbreak of norovirus infection masquerading as clostridium difficile infection.

Koo Hoonmo L HL   Ajami Nadim J NJ   Jiang Zhi-Dong ZD   Dupont Herbert L HL   Atmar Robert L RL   Lewis Debra D   Byers Patricia P   Abraham Paula P   Quijano Ricardo A RA   Musher Daniel M DM   Young Edward J EJ  

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090401 7


Noroviruses (NoVs) are increasingly being recognized as important enteric pathogens. At a university-based hospital, we investigated a nosocomial outbreak of NoV infection that was originally attributed to Clostridium difficile. We describe here the unique challenges of the identification of NoVs as the true etiologic pathogen in an outbreak occurring in a health care setting, where C. difficile infection is endemic, as well as the important lessons learned. ...[more]

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