Ontology highlight
ABSTRACT:
SUBMITTER: Irimia D
PROVIDER: S-EPMC3763906 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Integrative biology : quantitative biosciences from nano to macro 20081112 1
A major challenge in molecular biology is interrogating the human transcriptome on a genome wide scale when only a limited amount of biological sample is available for analysis. Current methodologies using microarray technologies for simultaneously monitoring mRNA transcription levels require nanogram amounts of total RNA. To overcome the sample size limitation of current technologies, we have developed a method to probe the global gene expression in biological samples as small as 150 cells, or ...[more]