Human growth is associated with distinct patterns of gene expression in evolutionarily conserved networks.
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ABSTRACT:
SUBMITTER: Stevens A
PROVIDER: S-EPMC3765282 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Human growth is associated with distinct patterns of gene expression in evolutionarily conserved networks.
Stevens Adam A Hanson Daniel D Whatmore Andrew A Destenaves Benoit B Chatelain Pierre P Clayton Peter P
BMC genomics 20130813
<h4>Background</h4>A co-ordinated tissue-independent gene expression profile associated with growth is present in rodent models and this is hypothesised to extend to all mammals. Growth in humans has similarities to other mammals but the return to active long bone growth in the pubertal growth spurt is a distinctly human growth event. The aim of this study was to describe gene expression and biological pathways associated with stages of growth in children and to assess tissue-independent express ...[more]
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