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Pharmacological treatments in ARDS; a state-of-the-art update.


ABSTRACT: Despite its high incidence and devastating outcomes, acute respiratory distress syndrome (ARDS) has no specific treatment, with effective therapy currently limited to minimizing potentially harmful ventilation and avoiding a positive fluid balance. Many pharmacological therapies have been investigated with limited success to date. In this review article we provide a state-of-the-art update on recent and ongoing trials, as well as reviewing promising future pharmacological therapies in ARDS.

SUBMITTER: Boyle AJ 

PROVIDER: S-EPMC3765621 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature

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Pharmacological treatments in ARDS; a state-of-the-art update.

Boyle Andrew James AJ   Mac Sweeney Rob R   McAuley Daniel Francis DF  

BMC medicine 20130820


Despite its high incidence and devastating outcomes, acute respiratory distress syndrome (ARDS) has no specific treatment, with effective therapy currently limited to minimizing potentially harmful ventilation and avoiding a positive fluid balance. Many pharmacological therapies have been investigated with limited success to date. In this review article we provide a state-of-the-art update on recent and ongoing trials, as well as reviewing promising future pharmacological therapies in ARDS. ...[more]

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