Risk factors for cisplatin-associated ototoxicity in pediatric oncology patients.
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ABSTRACT:
SUBMITTER: Yancey A
PROVIDER: S-EPMC3767972 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Publications
Risk factors for cisplatin-associated ototoxicity in pediatric oncology patients.
Yancey Allison A Harris Michael S MS Egbelakin Akinbode A Gilbert Jaimie J Pisoni David B DB Renbarger Jamie J
Pediatric blood & cancer 20120319 1
<h4>Background</h4>Cisplatin is an effective chemotherapy agent against several pediatric malignancies. One of its side effects is irreversible sensorineural hearing damage that is highly variable with a reported incidence of 22-70%. The aim of this study was to evaluate the incidence and identify clinical predictors of cisplatin-related ototoxicity.<h4>Procedures</h4>We performed a retrospective chart review of 102 pediatric patients who had completed cisplatin therapy for osteosarcoma, neurobl ...[more]
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