Ontology highlight
ABSTRACT:
SUBMITTER: Yuferov V
PROVIDER: S-EPMC3769182 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Annals of the New York Academy of Sciences 20100201
Addiction to opiates and illicit use of psychostimulants is a chronic, relapsing brain disease that, if left untreated, can cause major medical, social, and economic problems. This article reviews recent progress in studies of association of gene variants with vulnerability to develop opiate and cocaine addictions, focusing primarily on genes of the opioid and monoaminergic systems. In addition, we provide the first evidence of a cis-acting polymorphism and a functional haplotype in the PDYN gen ...[more]