Ontology highlight
ABSTRACT:
SUBMITTER: Jensen KJ
PROVIDER: S-EPMC3769421 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Physical biology 20120807 4
Cellular signal transduction is coordinated by modifications of many proteins within cells. Protein modifications are not independent, because some are connected through shared signaling cascades and others jointly converge upon common cellular functions. This coupling creates a hidden structure within a signaling network that can point to higher level organizing principles of interest to systems biology. One can identify important covariations within large-scale datasets by using mathematical m ...[more]