Ontology highlight
ABSTRACT:
SUBMITTER: Sedgmen BJ
PROVIDER: S-EPMC3770040 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Sedgmen B J BJ Papalia L L Wang L L Dyson A R AR McCallum H A HA Simson C M CM Pearse M J MJ Maraskovsky E E Hung D D Eomois P P PP Hartel G G Barnden M J MJ Rockman S P SP
Clinical & developmental immunology 20130826
The measurement of vaccine-induced humoral and CD4(+) and CD8(+) cellular immune responses represents an important correlate of vaccine efficacy. Accurate and reliable assays evaluating such responses are therefore critical during the clinical development phase of vaccines. T cells play a pivotal role both in coordinating the adaptive and innate immune responses and as effectors. During the assessment of cell-mediated immunity (CMI) in subjects participating in a large-scale influenza vaccine tr ...[more]