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4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia-zol-4-yl]phenol.

ABSTRACT: In the title compound, C14H15BrN2O2S, synthesized by the reaction of the corresponding phenacyl thio-cyanate with morpholine, the dihedral angle between the 1,3-thia-zole ring and the phenolic substituent ring is 23.46?(10)° as a result of the steric influence of the ortho-methyl group on the thia-zole ring. A strong intra-molecular phenolic O-H?N hydrogen bond is present in the mol-ecule. In the crystal, a weak C-H?Ophenol hydrogen bond gives rise to chains lying parallel to [20-1]. A short inter-molecular Br?Omorpholine inter-action is also present [3.1338?(19)?Å].

SUBMITTER: Bahrin LG

PROVIDER: S-EPMC3770429 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

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4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia-zol-4-yl]phenol.

Bahrin Lucian G LG Hrib Cristian G CG Birsa Lucian M LM

Acta crystallographica. Section E, Structure reports online 20130629 Pt 7

In the title compound, C14H15BrN2O2S, synthesized by the reaction of the corresponding phenacyl thio-cyanate with morpholine, the dihedral angle between the 1,3-thia-zole ring and the phenolic substituent ring is 23.46 (10)° as a result of the steric influence of the ortho-methyl group on the thia-zole ring. A strong intra-molecular phenolic O-H⋯N hydrogen bond is present in the mol-ecule. In the crystal, a weak C-H⋯Ophenol hydrogen bond gives rise to chains lying parallel to [20-1]. A short int ...[more]

PMID: 24046714

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