Ontology highlight
ABSTRACT:
SUBMITTER: Subramanian K
PROVIDER: S-EPMC3772055 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Subramanian Kartik K Paul Mark R MR Tyson John J JJ
PLoS computational biology 20130912 9
The free-living aquatic bacterium, Caulobacter crescentus, exhibits two different morphologies during its life cycle. The morphological change from swarmer cell to stalked cell is a result of changes of function of two bi-functional histidine kinases, PleC and CckA. Here, we describe a detailed molecular mechanism by which the function of PleC changes between phosphatase and kinase state. By mathematical modeling of our proposed molecular interactions, we derive conditions under which PleC, CckA ...[more]