Ontology highlight
ABSTRACT:
SUBMITTER: Petersdorf EW
PROVIDER: S-EPMC3772496 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Blood 20130722 11
Acute graft-versus-host disease (GVHD) afflicts as much as 80% of all patients who receive an unrelated donor hematopoietic cell transplant (HCT) for the treatment of blood disorders, even with optimal donor HLA matching and use of prophylactic immunosuppressive agents. Of patients who develop acute GVHD, many are at risk for chronic GVHD and bear the burden of considerable morbidity and lowered quality of life years after transplantation. The immunogenetic basis of GVHD has been the subject of ...[more]