Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen PK
PROVIDER: S-EPMC3774304 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Nguyen Peter K PK Snyder Christopher G CG Shields Jason D JD Smith Amanda W AW Elbert Donald L DL
Macromolecular chemistry and physics 20130401 8
Clickable poly(ethylene glycol) (PEG) derivatives are used with two sequential aqueous two-phase systems to produce microsphere-based scaffolds for cell encapsulation. In the first step, sodium sulfate causes phase separation of the clickable PEG precursors and is followed by rapid geleation to form microspheres in the absence of organic solvent or surfactant. The microspheres are washed and then deswollen in dextran solutions in the presence of cells, producing tightly packed scaffolds that can ...[more]