Ontology highlight
ABSTRACT:
SUBMITTER: Madsen DH
PROVIDER: S-EPMC3776354 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Madsen Daniel H DH Leonard Daniel D Masedunskas Andrius A Moyer Amanda A Jürgensen Henrik Jessen HJ Peters Diane E DE Amornphimoltham Panomwat P Selvaraj Arul A Yamada Susan S SS Brenner David A DA Burgdorf Sven S Engelholm Lars H LH Behrendt Niels N Holmbeck Kenn K Weigert Roberto R Bugge Thomas H TH
The Journal of cell biology 20130909 6
Tissue remodeling processes critically depend on the timely removal and remodeling of preexisting collagen scaffolds. Nevertheless, many aspects related to the turnover of this abundant extracellular matrix component in vivo are still incompletely understood. We therefore took advantage of recent advances in optical imaging to develop an assay to visualize collagen turnover in situ and identify cell types and molecules involved in this process. Collagen introduced into the dermis of mice underwe ...[more]