Imaging markers for Alzheimer disease: which vs how.
Ontology highlight
ABSTRACT:
SUBMITTER: Frisoni GB
PROVIDER: S-EPMC3776529 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Publications
Imaging markers for Alzheimer disease: which vs how.
Frisoni Giovanni B GB Frisoni Giovanni B GB Bocchetta Martina M Chételat Gael G Rabinovici Gil D GD de Leon Mony J MJ Kaye Jeffrey J Reiman Eric M EM Scheltens Philip P Barkhof Frederik F Black Sandra E SE Brooks David J DJ Carrillo Maria C MC Fox Nick C NC Herholz Karl K Nordberg Agneta A Jack Clifford R CR Jagust William J WJ Johnson Keith A KA Rowe Christopher C CC Sperling Reisa A RA Thies William W Wahlund Lars-Olof LO Weiner Michael W MW Pasqualetti Patrizio P Decarli Charles C
Neurology 20130701 5
Revised diagnostic criteria for Alzheimer disease (AD) acknowledge a key role of imaging biomarkers for early diagnosis. Diagnostic accuracy depends on which marker (i.e., amyloid imaging, ¹⁸F-fluorodeoxyglucose [FDG]-PET, SPECT, MRI) as well as how it is measured ("metric": visual, manual, semiautomated, or automated segmentation/computation). We evaluated diagnostic accuracy of marker vs metric in separating AD from healthy and prognostic accuracy to predict progression in mild cognitive impai ...[more]
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