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ABSTRACT:
SUBMITTER: Kuznetsov A
PROVIDER: S-EPMC3779490 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Organic letters 20130429 10
An efficient method for the synthesis of fused heteroaromatic dihydrosiloles via Ni-catalyzed hydrosilylation/intramolecular Ir-catalyzed dehydrogenative coupling of the Si-H bond with the heteroaromatic C-H bond has been developed. The method is efficient for both electron-deficient and -rich heterocycles. It exhibits high functional group tolerance and good regioselectivity. Fused heteroaromatic dihydrosiloles can be smoothly halogenated and then oxidized or arylated. Application of these tran ...[more]