Ontology highlight
ABSTRACT:
SUBMITTER: Clemm von Hohenberg C
PROVIDER: S-EPMC3780783 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Clemm von Hohenberg Christian C Wigand Marlene C MC Kubicki Marek M Leicht Gregor G Giegling Ina I Karch Susanne S Hartmann Annette M AM Konte Bettina B Friedl Marion M Ballinger Thomas T Eckbo Ryan R Bouix Sylvain S Jäger Lorenz L Shenton Martha E ME Rujescu Dan D Mulert Christoph C
Journal of psychiatric research 20130717 10
CNTNAP2 is a gene on chromosome 7 that has shown associations with autism and schizophrenia, and there is evidence that it plays an important role for neuronal synchronization and brain connectivity. In this study, we assessed the relationship between Diffusion Tensor Imaging (DTI), a putative marker of anatomical brain connectivity, and multiple single nucleotide polymorphisms (SNPs) spread out over this large gene. 81 healthy controls and 44 patients with schizophrenia (all Caucasian) underwen ...[more]