Ontology highlight
ABSTRACT:
SUBMITTER: Nghe P
PROVIDER: S-EPMC3782435 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Nghe Philippe P Boulineau Sarah S Gude Sebastian S Recouvreux Pierre P van Zon Jeroen S JS Tans Sander J SJ
PloS one 20130924 9
The ability to spatially confine living cells or small organisms while dynamically controlling their aqueous environment is important for a host of microscopy applications. Here, we show how polyacrylamide layers can be patterned to construct simple microfluidic devices for this purpose. We find that polyacrylamide gels can be molded like PDMS into micron-scale structures that can enclose organisms, while being permeable to liquids, and transparent to allow for microscopic observation. We presen ...[more]