Ontology highlight
ABSTRACT:
SUBMITTER: Stefansson H
PROVIDER: S-EPMC378543 | biostudies-literature | 2002 Oct
REPOSITORIES: biostudies-literature
Stefansson Hreinn H Sigurdsson Engilbert E Steinthorsdottir Valgerdur V Bjornsdottir Soley S Sigmundsson Thordur T Ghosh Shyamali S Brynjolfsson Jon J Gunnarsdottir Steinunn S Ivarsson Omar O Chou Thomas T TT Hjaltason Omar O Birgisdottir Birgitta B Jonsson Helgi H Gudnadottir Vala G VG Gudmundsdottir Elsa E Bjornsson Asgeir A Ingvarsson Brynjolfur B Ingason Andres A Sigfusson Sigmundur S Hardardottir Hronn H Harvey Richard P RP Lai Donna D Zhou Mingdong M Brunner Daniela D Mutel Vincent V Gonzalo Acuna A Lemke Greg G Sainz Jesus J Johannesson Gardar G Andresson Thorkell T Gudbjartsson Daniel D Manolescu Andrei A Frigge Michael L ML Gurney Mark E ME Kong Augustine A Gulcher Jeffrey R JR Petursson Hannes H Stefansson Kari K
American journal of human genetics 20020723 4
The cause of schizophrenia is unknown, but it has a significant genetic component. Pharmacologic studies, studies of gene expression in man, and studies of mouse mutants suggest involvement of glutamate and dopamine neurotransmitter systems. However, so far, strong association has not been found between schizophrenia and variants of the genes encoding components of these systems. Here, we report the results of a genomewide scan of schizophrenia families in Iceland; these results support previous ...[more]