Ontology highlight
ABSTRACT:
SUBMITTER: Kadiu I
PROVIDER: S-EPMC3786185 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Kadiu Irena I Narayanasamy Prabagaran P Dash Prasanta K PK Zhang Wei W Gendelman Howard E HE
Journal of immunology (Baltimore, Md. : 1950) 20120618 2
Exosomes and microvesicles (MV) are cell membranous sacs originating from multivesicular bodies and plasma membranes that facilitate long-distance intercellular communications. Their functional biology, however, remains incompletely understood. Macrophage exosomes and MV isolated by immunoaffinity and sucrose cushion centrifugation were characterized by morphologic, biochemical, and molecular assays. Lipidomic, proteomic, and cell biologic approaches uncovered novel processes by which exosomes ...[more]