Ontology highlight
ABSTRACT:
SUBMITTER: Blasius TL
PROVIDER: S-EPMC3786890 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Blasius T Lynne TL Reed Nathan N Slepchenko Boris M BM Verhey Kristen J KJ
PloS one 20130930 9
Kinesin motors drive the long-distance anterograde transport of cellular components along microtubule tracks. Kinesin-dependent transport plays a critical role in neurogenesis and neuronal function due to the large distance separating the soma and nerve terminal. The fate of kinesin motors after delivery of their cargoes is unknown but has been postulated to involve degradation at the nerve terminal, recycling via retrograde motors, and/or recycling via diffusion. We set out to test these models ...[more]