Ontology highlight
ABSTRACT:
SUBMITTER: Boyle SM
PROVIDER: S-EPMC3787389 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Boyle Sean Michael SM McInally Shane S Ray Anandasankar A
eLife 20131001
Coding of information in the peripheral olfactory system depends on two fundamental : interaction of individual odors with subsets of the odorant receptor repertoire and mode of signaling that an individual receptor-odor interaction elicits, activation or inhibition. We develop a cheminformatics pipeline that predicts receptor-odorant interactions from a large collection of chemical structures (>240,000) for receptors that have been tested to a smaller panel of odorants (∼100). Using a computati ...[more]