Ontology highlight
ABSTRACT:
SUBMITTER: Wielders PL
PROVIDER: S-EPMC3787816 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Wielders Pascal L M L PL Ludwig-Sengpiel Andrea A Locantore Nicholas N Baggen Suus S Chan Robert R Riley John H JH
The European respiratory journal 20130221 4
GSK961081 is a bifunctional molecule demonstrating both muscarinic antagonist and β-agonist activities. This was a 4-week, multicentre, randomised, double-blind, double-dummy, placebo and salmeterol controlled parallel group study. Doses ranging across three twice-daily doses and three once-daily doses were assessed in moderate and severe chronic obstructive pulmonary disease (COPD) patients. Trough forced expiratory volume in 1 s (FEV1) at day 29 was the primary end-point. At days 1 and 28, 12- ...[more]