Ontology highlight
ABSTRACT:
SUBMITTER: Denaro N
PROVIDER: S-EPMC3787923 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Denaro Nerina N Nigro Cristiana Lo CL Russi Elvio G EG Merlano Marco C MC
OncoTargets and therapy 20130916
Anaplastic thyroid cancer represents 1%-2% of thyroid cancers. For its aggressiveness, it is considered a systemic disease at the time of diagnosis. Surgery remains the cornerstone of therapy in resectable tumor. Traditional chemotherapy has little effect on metastatic disease. A multimodality approach, incorporating cytoreductive surgical resection, chemoradiation, either concurrently or sequentially, and new promising target therapies is advisable. Doxorubicin is the most commonly used agent, ...[more]