Ontology highlight
ABSTRACT:
SUBMITTER: Moskowitz CH
PROVIDER: S-EPMC3790950 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Moskowitz Craig H CH Matasar Matt J MJ Zelenetz Andrew D AD Nimer Stephen D SD Gerecitano John J Hamlin Paul P Horwitz Steven S Moskowitz Alison J AJ Noy Ariela A Palomba Lia L Perales Miguel-Angel MA Portlock Carol C Straus David D Maragulia Jocelyn C JC Schoder Heiko H Yahalom Joachim J
Blood 20111219 7
We previously reported that remission duration < 1 year, extranodal disease, and B symptoms before salvage chemotherapy (SLT) can stratify relapsed or refractory Hodgkin lymphoma (HL) patients into favorable and unfavorable cohorts. In addition, pre-autologous stem cell transplant (ASCT) (18)FDG-PET response to SLT predicts outcome. This phase 2 study uses both pre-SLT prognostic factors and post-SLT FDG-PET response in a risk-adapted approach to improve PFS after high-dose radio-chemotherapy (H ...[more]