Ontology highlight
ABSTRACT:
SUBMITTER: Zhang M
PROVIDER: S-EPMC3792662 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Zhang Min M Xu Han-Yang HY Wang Yi-Cui YC Shi Zhu-Bing ZB Zhang Nan-Nan NN
Acta crystallographica. Section F, Structural biology and crystallization communications 20130928 Pt 10
Succinyl-CoA:3-ketoacid CoA transferase (SCOT) plays a crucial role in ketone-body metabolism. SCOT from Drosophila melanogaster (DmSCOT) was purified and crystallized. The crystal structure of DmSCOT was determined at 2.64 Å resolution and belonged to space group P212121, with unit-cell parameters a=76.638, b=101.921, c=122.457 Å, α=β=γ=90°. Sequence alignment and structural analysis identified DmSCOT as a class I CoA transferase. Compared with Acetobacter aceti succinyl-CoA:acetate CoA transfe ...[more]