Host genes associated with HIV/AIDS: advances in gene discovery.
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ABSTRACT:
SUBMITTER: An P
PROVIDER: S-EPMC3792714 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Publications
Host genes associated with HIV/AIDS: advances in gene discovery.
Trends in genetics : TIG 20100210 3
Twenty-five years after the discovery of HIV as the cause of AIDS there is still no effective vaccine and no cure for this disease. HIV susceptibility shows a substantial degree of individual heterogeneity, much of which can be conferred by host genetic variation. In an effort to discover host factors required for HIV replication, identify crucial pathogenic pathways, and reveal the full armament of host defenses, there has been a shift from candidate-gene studies to unbiased genome-wide genetic ...[more]
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