Ontology highlight
ABSTRACT:
SUBMITTER: Nakanishi H
PROVIDER: S-EPMC379277 | biostudies-literature | 2004 Apr
REPOSITORIES: biostudies-literature
Nakanishi Hideki H de los Santos Pablo P Neiman Aaron M AM
Molecular biology of the cell 20040123 4
In Saccharomyces cerevisiae, the developmentally regulated Soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) protein Spo20p mediates the fusion of vesicles with the prospore membrane, which is required for the formation of spores. Spo20p is subject to both positive and negative regulation by separate sequences in its aminoterminal domain. We report that the positive activity is conferred by a short, amphipathic helix that is sufficient to confer plasma membrane or pro ...[more]