Ontology highlight
ABSTRACT:
SUBMITTER: Janes DE
PROVIDER: S-EPMC3798014 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Janes D E DE Elsey R M RM Langan E M EM Valenzuela N N Edwards S V SV
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 20130508 5
Across amniotes, sex-determining mechanisms exhibit great variation, yet the genes that govern sexual differentiation are largely conserved. Studies of evolution of sex-determining and sex-differentiating genes require an exhaustive characterization of functions of those genes such as FOXL2 and FGF9. FOXL2 is associated with ovarian development, and FGF9 is known to play a role in testicular organogenesis in mammals and other amniotes. As a step toward characterization of the evolutionary histor ...[more]